Grandma's Boy (20th Century Fox, 2006)

After a careless roommate blows months' worth of back rent on Filipina hookers, video game tester Alex (Allen Covert) is forced to find new living arrangements. He turns to his dope-dealing friend Dante (Peter Dante), but this conflicts with the arrival of a lion that will "protect the shit" and keep the taekwondo-practicing monkey at bay. Luckily, co-worker Jeff (Nick Swardson) offers Alex the use of an air mattress for the night, but an accident involving Jeff's mom and a sticky substance puts the vagabond out the door again. Shelter's answer comes in the form of Grandma Lilly (Doris Roberts), who shares her quaint home with two elderly ladies. Bea (Shirley Knight) dines on pills with syrup for breakfast and licks paintbrushes. In between wisecracks, Grace (Shirley Jones) is a perpetually horny GILF who has "given Charlie Chaplin a handjob" and "69'd Don Knotts." At first, Alex is handed a laundry list of household chores, but the gift of an illegal cable box satiates the women and gives him the opportunity to work on an upcoming title (Eternal Death Slayer 3) for Branasium. Overseeing the project is Samantha (Linda Cardellini), who name-drops Super Mario Brothers and has big mushroom eyes for Alex. This power-up makes a jealous Bowser out of J.P. (Joel David Moore) -- a Marilyn Manson-cum-Urkel prodigy who created the game currently demanding the company's attention. Not being invited to an impromptu party that showcases Samantha singing Salt 'N' Pepa, he spins 'n' sobs a story to Alex about "wanting people to like him." Tears and snot wiped away, J.P. extends help on a non-Branasium game Alex has been developing for years. Problems with EDS 3 and the Samantha situation lead J.P. to claim Alex's work as his own at the unveiling. Can Alex use the secret weapon to slay the dragon and get the girl?